The known is finite, the unknown infinite; intellectually we stand on an islet in the midst of an illimitable ocean of inexplicability. Our business in every generation is to reclaim a little more land, to add something to the extent and the solidity of our possessions. And even a cursory glance at the history of the biological sciences during the last quarter of a century is sufficient to justify the assertion, that the most potent instrument for the extension of the realm of natural knowledge which has come into men's hands, since the publication of Newton's 'Principia,' is Darwin's 'Origin of Species.'

It was badly received by the generation to which it was first addressed, and the outpouring of angry nonsense to which it gave rise is sad to think upon. But the present generation will probably behave just as badly if another Darwin should arise, and inflict upon them that which the generality of mankind most hate – the necessity of revising their convictions. -- ThomasHenryHuxley

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These times are the ancient times, when the world is ancient, and not those which we account ancient ''ordine retrogrado'', by a computation backward from ourselves. -- FrancisBacon

'''The Idea of Progress'''

That history might in fact be progressive, i.e., an onward and upward ascent – and not, as MrAristotle had taught, merely cyclical or, as cultural pessimists from Hesiod to Spengler have supposed, a descending or retrograde movement - became for Bacon an article of secular faith which he propounded with evangelical force and a sense of mission. In the Advancement, the idea is offered tentatively, as a kind of hopeful hypothesis. But in later works such as the New Organon, it becomes almost a promised destiny: Enlightenment and a better world, Bacon insists, lie within our power; they require only the cooperation of learned citizens and the active development of the arts and sciences.

(From http://www.iep.utm.edu/b/bacon.htm)

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If I have seen further, it is by standing on the ShouldersOfGiants. -- IsaacNewton 

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There are some things which cannot be learned quickly, and time, which is all we have, must be paid heavily for their acquiring. They are the very simplest things, and because it takes a man's life to know them the little new that each man gets from life is very costly and the only heritage he has to leave. -- ErnestHemingway