PragmaticSmalltalk is a dialect of SmalltalkLanguage closely tied to EtoileOs.  It interoperates very cleanly (and fast) with the EtoileOs frameworks (which are improved versions of the GnuStep frameworks) and with CeeSharp.

See http://etoileos.com/news/archive/2012/08/19/1308/ for some example code.
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CategorySmalltalk